Nicotine-based ionic liquid: as a green catalyst for pyridine-catalyzed Huisgen reaction

Authors

  • Ahmed Ali Hullio Dr. M.A Kazi Institute of chemistry, University of Sindh Jamshoro-76080, Pakistan.
  • Ghulam Murtaza Mastoi Dr. M.A Kazi Institute of chemistry, University of Sindh Jamshoro-76080, Pakistan.
Abstract:

Nicotine-based ionic liquid has been used as a green catalyst for pyridine-catalyzed Huisgen reaction. It promoted addition of dimethylacetylenedicarboxylate to aldehydes or N-tosyl imines leading to efficient synthesis of 2-benzoylfumarates and 1-azadienes respectively under pyridine free odorless ionic liquid conditions. The improved results were obtained in terms of enhanced yields, with minimal work up.

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Journal title

volume 2  issue 4

pages  165- 171

publication date 2012-12-01

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